Impact of Plasma p-tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS.
Overview
and 6 other authors
Frederic Brosseron11, Matthias C Schmid11,22, Anja Schneider11,21, Stefan Teipel2,23, Johannes Prudlo1,2, Andreas Hermann2,323 affiliations
- Department of Neurology, Rostock University Medical Center, Rostock, Germany
- German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Germany
- Translational Neurodegeneration Section “Albrecht Kossel”, Department of Neurology, Rostock University Medical Center, Rostock, Germany
- German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany
- Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin‐Institute of Psychiatry and Psychotherapy, Berlin, Germany
- Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany
- ECRC Experimental and Clinical Research Center, Charité—Universitätsmedizin Berlin, Berlin, Germany
- Neuropsychiatry and Laboratory of Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Charité—Universitätsmedizin Berlin, Berlin, Germany
- Department of Psychiatry and Psychotherapy, School of Medicine and Health, Technical University of Munich, and German Center for Mental Health (DZPG), Munich, Germany
- University of Edinburgh and UK DRI, Edinburgh, UK
- German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
- Department of Vascular Neurology, University Hospital Bonn, Bonn, Germany
- Department of Neurology, University of Bonn, Bonn, Germany
- German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany
- Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany
- Institute of Cognitive Neurology and Dementia Research, Otto‐von‐Guericke University, Magdeburg, Germany
- Institute of Cognitive Neuroscience, University College London, London, UK
- German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
- Division of Translational Genomics of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany
- Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany
- Institute for Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany
- Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany
Abstract
Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/
Reproduced under the paper's license (CC BY), from the paper cited above.
Code
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The paper's code and data availability statement is in the Data section.
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Data
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Data Availability Statement
Anonymized data and scripts used for the current study are available from the corresponding author upon reasonable request.
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 2, 28 September 2026
- Funding: added Eli Lilly and Company
Version 1, 28 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 26 authors, 3 keywords, 14 MeSH terms, 21 references.
Cite
This paper
Kasper, E., Lehto, A., Nordmann, N., Peters, O., Hellmann, J., Priller, J., Spruth, E. J., Petzold, G. C., Vogt, I., Weydt, P., Bernsen, S., Dinter, E., Falkenburger, B., Günther, R., Düzel, E., Glanz, W., Synofzik, M., Beichert, L., Spottke, A., . . . Hermann, A. (2026). Impact of Plasma p-tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS. Annals of clinical and translational neurology, 13(8), 1711-1718. https://
BibTeX
@article{kasper2026impac
author = {Kasper, Elisabeth and Lehto, Annaliis and Nordmann, Nina and Peters, Oliver and Hellmann, Julian and Priller, Josef and Spruth, Eike Jakob and Petzold, Gabor C and Vogt, Ina and Weydt, Patrick and Bernsen, Sarah and Dinter, Elisabeth and Falkenburger, Björn and Günther, René and Düzel, Emrah and Glanz, Wenzel and Synofzik, Matthis and Beichert, Lukas and Spottke, Annika and Wagner, Michael and Brosseron, Frederic and Schmid, Matthias C and Schneider, Anja and Teipel, Stefan and Prudlo, Johannes and Hermann, Andreas},
title = {{Impact of Plasma p-tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS}},
journal = {Annals of clinical and translational neurology},
year = {2026},
month = may,
volume = {13},
number = {8},
pages = {1711--1718},
publisher = {Wiley},
issn = {2328-9503},
doi = {10.1002/
url = {https://
pmid = {42080410},
pmcid = {PMC13395029}
}
RIS
TY - JOUR
AU - Kasper, Elisabeth
AU - Lehto, Annaliis
AU - Nordmann, Nina
AU - Peters, Oliver
AU - Hellmann, Julian
AU - Priller, Josef
AU - Spruth, Eike Jakob
AU - Petzold, Gabor C
AU - Vogt, Ina
AU - Weydt, Patrick
AU - Bernsen, Sarah
AU - Dinter, Elisabeth
AU - Falkenburger, Björn
AU - Günther, René
AU - Düzel, Emrah
AU - Glanz, Wenzel
AU - Synofzik, Matthis
AU - Beichert, Lukas
AU - Spottke, Annika
AU - Wagner, Michael
AU - Brosseron, Frederic
AU - Schmid, Matthias C
AU - Schneider, Anja
AU - Teipel, Stefan
AU - Prudlo, Johannes
AU - Hermann, Andreas
TI - Impact of Plasma p-tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS
T2 - Annals of clinical and translational neurology
J2 - Ann Clin Transl Neurol
PY - 2026
DA - 2026/
VL - 13
IS - 8
SP - 1711
EP - 1718
SN - 2328-9503
PB - Wiley
DO - 10.1002/
UR - https://
LA - en
ER -
CSL-JSON
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