OSCR

Genetic dissection of the role of <i>Piga</i> and <i>Pgap2</i> in the embryonic mouse brain.

Overview

Authors: Jennifer L Watts1, Jesus M Leal1, Rolf W Stottmann1,2
  1. Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH 43215, USA
  2. Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH 43210, USA
Institutions: Nationwide Children's Hospital (United States); The Ohio State University (United States)
Journal: iScience, volume 29, issue 6, article 116299
Dates: received 26 December 2025; accepted 22 May 2026; published online 9 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.isci.2026.116299 · PMID 42317730 · PMCID PMC13273472 · OpenAlex W4417251707
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: mouse (organism)
Methods: Statistics
Keywords: molecular genetics, molecular biology, neuroscience
Topic: Neurological diseases and metabolism (Neurology, Neuroscience), according to OpenAlex
Funding: Abigail Wexner Research Institute at Nationwide Children's Hospital
Citations: not cited yet (Europe PMC); 93 references in the paper
Research resources: Rabbit anti-CTIP2 RRID:AB_1140055, RRID:AB_143165, Rabbit anti-CUX1 RRID:AB_2086995, goat anti-chicken antibody RRID:AB_2313506, Rat anti-Myelin Basic Protein RRID:AB_2313550, RRID:AB_2535849, Rabbite anti-SKOR2 RRID:AB_2632379, Rabbit anti-CONTACTIN1 RRID:AB_2768975, Rabbit anti-PDGFRα RRID:AB_2892065, Rabbit anti-PAX6 RRID:AB_305110, Rabbit anti-CALBINDIN RRID:AB_448597, Mouse: Pgap2tm1a(EUCOMM)Wtsi RRID:IMSR_EM:09276, RRID:IMSR_JAX:005628, Mouse: En1-Cre; En1tm2(cre)Wrst/J RRID:IMSR_JAX:007916, RRID:IMSR_JAX:025567, Mouse: Pigaflox/X or B6.129-Pigatm1 RRID:IMSR_RBRC06211, Prism GraphPad v10.6.0 RRID:SCR_002798, ZEN Microscopy Software RRID:SCR_013672, NIS Elements RRID:SCR_014329, RRID:SCR_024706, RRID:SCR_027509

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

Tracing map

A tracing map links a paper to the code its authors published: this paper has none (its code is available on request), so it has no map.

Data

No dataset and no data link were found in the paper.

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.isci.2026.116299.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 3 authors, 3 keywords, 1 funder, 91 references, 21 RRIDs.

Cite

This paper

Watts, J. L., Leal, J. M., & Stottmann, R. W. (2026). Genetic dissection of the role of <i>Piga</i> and <i>Pgap2</i> in the embryonic mouse brain. iScience, 29(6), 116299. https://doi.org/10.1016/j.isci.2026.116299

BibTeX

@article{watts2026genetic,
author = {Watts, Jennifer L and Leal, Jesus M and Stottmann, Rolf W},
title = {{Genetic dissection of the role of \<i\>Piga\</i\> and \<i\>Pgap2\</i\> in the embryonic mouse brain}},
journal = {iScience},
year = {2026},
month = jun,
volume = {29},
number = {6},
pages = {116299},
publisher = {Elsevier},
issn = {2589-0042},
doi = {10.1016/j.isci.2026.116299},
url = {https://doi.org/10.1016/j.isci.2026.116299},
pmid = {42317730},
pmcid = {PMC13273472}
}

RIS

TY - JOUR
AU - Watts, Jennifer L
AU - Leal, Jesus M
AU - Stottmann, Rolf W
TI - Genetic dissection of the role of <i>Piga</i> and <i>Pgap2</i> in the embryonic mouse brain
T2 - iScience
J2 - iScience
PY - 2026
DA - 2026/06/09
VL - 29
IS - 6
SP - 116299
SN - 2589-0042
PB - Elsevier
DO - 10.1016/j.isci.2026.116299
UR - https://doi.org/10.1016/j.isci.2026.116299
LA - en
ER -

CSL-JSON

{
"id": "10.1016/j.isci.2026.116299",
"type": "article-journal",
"title": "Genetic dissection of the role of <i>Piga</i> and <i>Pgap2</i> in the embryonic mouse brain",
"container-title": "iScience",
"author": [
{
"family": "Watts",
"given": "Jennifer L"
},
{
"family": "Leal",
"given": "Jesus M"
},
{
"family": "Stottmann",
"given": "Rolf W"
}
],
"container-title-short": "iScience",
"volume": "29",
"issue": "6",
"page": "116299",
"DOI": "10.1016/j.isci.2026.116299",
"PMID": "42317730",
"PMCID": "PMC13273472",
"ISSN": "2589-0042",
"publisher": "Elsevier",
"URL": "https://doi.org/10.1016/j.isci.2026.116299",
"language": "en",
"issued": {
"date-parts": [
[
2026,
6,
9
]
]
}
}

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1016/j.ebiom.2026.106309
An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice.
Journal: EBioMedicine
In common: mouse, 2 references
[2] doi:10.1016/j.isci.2026.116975
Loss of YY1 in Purkinje cells triggers cerebellar ataxia via Wnt10b-mediated impairment of dendrite development.
Journal: iScience
In common: 2 references
[3] doi:10.1038/s41467-026-71919-6 [code]
Suppression of astrocyte BMP signaling improves molecular signatures and functional deficits in a fragile X syndrome mouse model.
Journal: Nature communications
In common: mouse, 2 references
[4] doi:10.1002/glia.70142
The Ubiquitin Ligase Zinc Finger SWIM Domain-Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA-7 Axis.
Journal: Glia
In common: mouse, 2 references
[5] doi:10.3389/fncel.2026.1832157
Histone demethylase KDM6B promotes postnatal oligodendrocyte maturation and cortical myelination.
Journal: Frontiers in cellular neuroscience
In common: 2 references
[6] doi:10.1038/s41598-026-54112-z
Optimized nuclei isolation and snRNA-seq reveal oligodendrocyte pathway dysregulation in MOGHE brain tissue from pediatric patients.
Journal: Scientific reports
In common: 2 references
[7] doi:10.1021/acs.jmedchem.6c01882
Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 Proteinopathy.
Journal: Journal of medicinal chemistry
In common: mouse, 1 reference
[8] doi:10.1038/s41467-026-75700-7 [code]
Gene regulatory innovations from transposable elements in primate cerebellum development.
Journal: Nature communications
In common: mouse, 1 reference
[9] doi:10.1186/s12929-026-01257-8
Distinct and combined interferon-ɑ/β-receptor-1 loss in neurons and astrocytes disrupt brain energy metabolism and drive Parkinsonian dementia.
Journal: Journal of biomedical science
In common: mouse, 1 reference
[10] doi:10.1242/dev.205423 [code]
CSF1R+ macrophage and osteoclast depletion impairs neural crest proliferation and craniofacial morphogenesis.
Journal: Development (Cambridge, England)
In common: mouse, 1 reference

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.