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The Ubiquitin Ligase Zinc Finger SWIM Domain-Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA-7 Axis.

Overview

Authors: Jing Lei1,2,3, Siming Zhong4,5, Rong Fan6, Xin Shu7, Guan Wang2,3, Jiansheng Guo8, Shuting Xue7, Luqian Zheng7, Aiming Ren7, Junfang Ji7, Bing Yang7, Shumin Duan2,3, Zhiping Wang2,3, Xing Guo7
ORCID iDs: Siming Zhong, Jiansheng Guo
  1. International Institutes of Medicine The Fourth Affiliated Hospital of Zhejiang University School of Medicine Yiwu China
  2. Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology Zhejiang University School of Medicine Hangzhou China
  3. The MOE Frontier Science Center for Brain Research and Brain‐Machine Integration Zhejiang University School of Brain Science and Brain Medicine Hangzhou China
  4. Zhejiang University‐University of Edinburgh Institute Zhejiang University Haining China
  5. Deanery of Biomedical Sciences, College of Medicine and Veterinary Medicine University of Edinburgh Edinburgh UK
  6. College of Life Science Zhejiang University Hangzhou China
  7. Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute Zhejiang University Hangzhou China
  8. Center of Cryo‐Electron Microscopy Zhejiang University Hangzhou China
Institutions: Second Affiliated Hospital of Zhejiang University (China); Zhejiang University (China); Zhejiang University-University of Edinburgh Institute (China); University of Edinburgh (United Kingdom)
Journal: Glia, volume 74, issue 5, article e70142
Dates: received 25 April 2025; accepted 29 January 2026; published online 5 March 2026; in print May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1002/glia.70142 · PMID 41787678 · PMCID PMC12963713 · OpenAlex W7134070746
Open access: hybrid, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism), cellular / molecular (subfield)
Methods: Statistics
Keywords: AGO2, E3 ubiquitin ligase, ELAV1, intrinsically disordered region, MiR7, myelination, oligodendrocyte development, oligodendrocyte progenitor cells, ZSWIM8
MeSH: Argonaute Proteins*, MicroRNAs*, Oligodendroglia*, Ubiquitin-Protein Ligases*, Animals, Brain, Gene Expression Regulation, Developmental, Mice, Mice, Knockout, Myelin Sheath (* major topic)
Topic: MicroRNA in disease regulation (Cancer Research, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: National Natural Science Foundation of China (31671039, 32071257); National Key Research and Development Program of China (2016YFA0501000, 2023YFF1204400)
Citations: not cited yet (Europe PMC); 77 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Tracing map

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Data

Datasets cited

Data availability statement

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Read it in the paper: doi.org/10.1002/glia.70142.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Publisher: n/a → Wiley

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 14 authors, 9 keywords, 10 MeSH terms, 2 funders, 77 references.

Cite

This paper

Lei, J., Zhong, S., Fan, R., Shu, X., Wang, G., Guo, J., Xue, S., Zheng, L., Ren, A., Ji, J., Yang, B., Duan, S., Wang, Z., & Guo, X. (2026). The Ubiquitin Ligase Zinc Finger SWIM Domain-Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA-7 Axis. Glia, 74(5), e70142. https://doi.org/10.1002/glia.70142

BibTeX

@article{lei2026ubiquitin,
author = {Lei, Jing and Zhong, Siming and Fan, Rong and Shu, Xin and Wang, Guan and Guo, Jiansheng and Xue, Shuting and Zheng, Luqian and Ren, Aiming and Ji, Junfang and Yang, Bing and Duan, Shumin and Wang, Zhiping and Guo, Xing},
title = {{The Ubiquitin Ligase Zinc Finger SWIM Domain-Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA-7 Axis}},
journal = {Glia},
year = {2026},
month = may,
volume = {74},
number = {5},
pages = {e70142},
publisher = {Wiley},
issn = {0894-1491},
doi = {10.1002/glia.70142},
url = {https://doi.org/10.1002/glia.70142},
pmid = {41787678},
pmcid = {PMC12963713}
}

RIS

TY - JOUR
AU - Lei, Jing
AU - Zhong, Siming
AU - Fan, Rong
AU - Shu, Xin
AU - Wang, Guan
AU - Guo, Jiansheng
AU - Xue, Shuting
AU - Zheng, Luqian
AU - Ren, Aiming
AU - Ji, Junfang
AU - Yang, Bing
AU - Duan, Shumin
AU - Wang, Zhiping
AU - Guo, Xing
TI - The Ubiquitin Ligase Zinc Finger SWIM Domain-Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA-7 Axis
T2 - Glia
J2 - Glia
PY - 2026
DA - 2026/05/01
VL - 74
IS - 5
SP - e70142
SN - 0894-1491
PB - Wiley
DO - 10.1002/glia.70142
UR - https://doi.org/10.1002/glia.70142
LA - en
ER -

CSL-JSON

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