OSCR

Promoting donor microglial replacement through augmented conditioning or radiation sensitivity.

Overview

Authors: Troy C Lund1, Willa Durose1, Emma Schindhelm1, Megan M Constans1, Erin E Nolan1, Ashish O Gupta1, Kai Braaten1, Paul J Orchard1
ORCID iDs: Troy C Lund, Paul J Orchard
  1. Department of Pediatrics, Division of Pediatric Blood and Marrow Transplantation & Cellular Therapy, Minneapolis, MN 55455, USA
Journal: Molecular therapy : the journal of the American Society of Gene Therapy, volume 34, issue 7, pages 3756-3762
Dates: received 17 September 2025; accepted 2 April 2026; published online 12 April 2026; in print 1 July 2026
Type: Brief report · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.ymthe.2026.04.012 · PMID 41968582 · PMCID PMC13330021 · OpenAlex W7153802326
Open access: hybrid, a free copy (OpenAlex)
Status: code on request
Categories: mouse (organism), cellular / molecular (subfield)
Methods: Evoked potentials
Keywords: hematopoietic cell transplantation, microglia, brain, radiation, DNA damage
MeSH: Hematopoietic Stem Cell Transplantation*, Microglia*, Radiation Tolerance*, Transplantation Conditioning*, Animals, Brain, Busulfan, Graft Survival, Mice, Mice, Inbred C57BL, Myeloid Cells (* major topic)
Topic: Neuroinflammation and Neurodegeneration Mechanisms (Neurology, Neuroscience), according to OpenAlex
Citations: cited by 1 paper (Europe PMC); 25 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.ymthe.2026.04.012.

Versions

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Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 5 keywords, 11 MeSH terms, 25 references.

Cite

This paper

Lund, T. C., Durose, W., Schindhelm, E., Constans, M. M., Nolan, E. E., Gupta, A. O., Braaten, K., & Orchard, P. J. (2026). Promoting donor microglial replacement through augmented conditioning or radiation sensitivity. Molecular therapy : the journal of the American Society of Gene Therapy, 34(7), 3756-3762. https://doi.org/10.1016/j.ymthe.2026.04.012

BibTeX

@article{lund2026promoting,
author = {Lund, Troy C and Durose, Willa and Schindhelm, Emma and Constans, Megan M and Nolan, Erin E and Gupta, Ashish O and Braaten, Kai and Orchard, Paul J},
title = {{Promoting donor microglial replacement through augmented conditioning or radiation sensitivity}},
journal = {Molecular therapy : the journal of the American Society of Gene Therapy},
year = {2026},
month = apr,
volume = {34},
number = {7},
pages = {3756--3762},
publisher = {American Society of Gene \& Cell Therapy},
issn = {1525-0016},
doi = {10.1016/j.ymthe.2026.04.012},
url = {https://doi.org/10.1016/j.ymthe.2026.04.012},
pmid = {41968582},
pmcid = {PMC13330021}
}

RIS

TY - JOUR
AU - Lund, Troy C
AU - Durose, Willa
AU - Schindhelm, Emma
AU - Constans, Megan M
AU - Nolan, Erin E
AU - Gupta, Ashish O
AU - Braaten, Kai
AU - Orchard, Paul J
TI - Promoting donor microglial replacement through augmented conditioning or radiation sensitivity
T2 - Molecular therapy : the journal of the American Society of Gene Therapy
J2 - Mol Ther
PY - 2026
DA - 2026/04/12
VL - 34
IS - 7
SP - 3756
EP - 3762
SN - 1525-0016
PB - American Society of Gene & Cell Therapy
DO - 10.1016/j.ymthe.2026.04.012
UR - https://doi.org/10.1016/j.ymthe.2026.04.012
LA - en
ER -

CSL-JSON

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"language": "en",
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