OSCR

FLVCR2 Regulation of Intracellular Heme Modulates Vascular Tip/Stalk Specification During Retinal Angiogenesis.

Overview

Authors: Andreia Goncalves1, Alexander Stanley1, Nicolas Santander2, Dibyanti Mukherjee3, Xuwen Liu1, Audrey Cleuren4, Thomas Arnold3, David Antonetti1
ORCID iDs: Nicolas Santander, Xuwen Liu
  1. Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, United States
  2. Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile
  3. Department of Pediatrics, University of California San Francisco, San Francisco, California, United States
  4. Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States
Institutions: University of Michigan (United States); University of O'Higgins (Chile); University of California, San Francisco (United States); Oklahoma Medical Research Foundation (United States)
Journal: Investigative ophthalmology & visual science, volume 67, issue 8, article 32
Dates: received 17 April 2026; accepted 15 June 2026; published online 10 July 2026; in print July 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1167/iovs.67.8.32 · PMID 42429482 · PMCID PMC13372061 · OpenAlex W7167923114
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism), other (organism), cellular / molecular (subfield)
Keywords: angiogenesis, heme, tip/stalk specification, CNS vascularization, FLVCR2
MeSH: Heme*, Membrane Transport Proteins*, Receptors, Virus*, Retinal Neovascularization*, Retinal Vessels*, Animals, Blotting, Western, Cattle, Cells, Cultured, Disease Models, Animal, Endothelium, Vascular, Mice, Mice, Knockout, Signal Transduction (* major topic)
Topic: Retinal Development and Disorders (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: NIH HHS (S10 OD028612); NEI NIH HHS (P30 EY007003, R01 EY034615, F31 EY007003); NINDS NIH HHS (R01 NS123168)
Citations: not cited yet (Europe PMC); 43 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 5 keywords, 14 MeSH terms, 3 funders, 43 references.

Cite

This paper

Goncalves, A., Stanley, A., Santander, N., Mukherjee, D., Liu, X., Cleuren, A., Arnold, T., & Antonetti, D. (2026). FLVCR2 Regulation of Intracellular Heme Modulates Vascular Tip/Stalk Specification During Retinal Angiogenesis. Investigative ophthalmology & visual science, 67(8), 32. https://doi.org/10.1167/iovs.67.8.32

BibTeX

@article{goncalves2026flvcr2,
author = {Goncalves, Andreia and Stanley, Alexander and Santander, Nicolas and Mukherjee, Dibyanti and Liu, Xuwen and Cleuren, Audrey and Arnold, Thomas and Antonetti, David},
title = {{FLVCR2 Regulation of Intracellular Heme Modulates Vascular Tip/Stalk Specification During Retinal Angiogenesis}},
journal = {Investigative ophthalmology \& visual science},
year = {2026},
month = jul,
volume = {67},
number = {8},
pages = {32},
publisher = {Association for Research in Vision and Ophthalmology},
issn = {0146-0404},
doi = {10.1167/iovs.67.8.32},
url = {https://doi.org/10.1167/iovs.67.8.32},
pmid = {42429482},
pmcid = {PMC13372061}
}

RIS

TY - JOUR
AU - Goncalves, Andreia
AU - Stanley, Alexander
AU - Santander, Nicolas
AU - Mukherjee, Dibyanti
AU - Liu, Xuwen
AU - Cleuren, Audrey
AU - Arnold, Thomas
AU - Antonetti, David
TI - FLVCR2 Regulation of Intracellular Heme Modulates Vascular Tip/Stalk Specification During Retinal Angiogenesis
T2 - Investigative ophthalmology & visual science
J2 - Invest Ophthalmol Vis Sci
PY - 2026
DA - 2026/07/01
VL - 67
IS - 8
SP - 32
SN - 0146-0404
PB - Association for Research in Vision and Ophthalmology
DO - 10.1167/iovs.67.8.32
UR - https://doi.org/10.1167/iovs.67.8.32
LA - en
ER -

CSL-JSON

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"container-title": "Investigative ophthalmology & visual science",
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"PMCID": "PMC13372061",
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"publisher": "Association for Research in Vision and Ophthalmology",
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"language": "en",
"issued": {
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