Integrated analysis of single-cell transcriptome identifies a glial-neurovascular signaling trajectory in brain repair after ischemia.
Overview
- Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
- Department of Neurosurgery, Trauma Medical Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China
- State Key Laboratory of Common Mechanism Research for Major Diseases, Beijing, China
Abstract
The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.
Code
The paper links to its data, not to its authors' code: see the Data section.
Tracing map
A tracing map links a paper to the code its authors published: this paper has none, so it has no map.
Data
Datasets cited
- geo:GSE250245, at NCBI GEO; found in “Data availability”
Data availability statement
The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:
- it points to a dataset: NCBI GEO GSE250245
Read it in the paper: doi.org/10.1186/s13062-026-00912-2.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 5 keywords, 11 MeSH terms, 4 funders, 102 references.
Cite
This paper
Liu, H., Li, Z., Geng, R., Gu, L., & Bao, X. (2026). Integrated analysis of single-cell transcriptome identifies a glial-neurovascular signaling trajectory in brain repair after ischemia. Biology direct, 21(1), 168. https://
BibTeX
@article{liu2026integrat
author = {Liu, Hanyou and Li, Zhenwei and Geng, Ruxu and Gu, Lingui and Bao, Xinjie},
title = {{Integrated analysis of single-cell transcriptome identifies a glial-neurovascular signaling trajectory in brain repair after ischemia}},
journal = {Biology direct},
year = {2026},
month = sep,
volume = {21},
number = {1},
pages = {168},
publisher = {BMC},
issn = {1745-6150},
doi = {10.1186/
url = {https://
pmid = {42706574},
pmcid = {PMC13548491}
}
RIS
TY - JOUR
AU - Liu, Hanyou
AU - Li, Zhenwei
AU - Geng, Ruxu
AU - Gu, Lingui
AU - Bao, Xinjie
TI - Integrated analysis of single-cell transcriptome identifies a glial-neurovascular signaling trajectory in brain repair after ischemia
T2 - Biology direct
J2 - Biol Direct
PY - 2026
DA - 2026/
VL - 21
IS - 1
SP - 168
SN - 1745-6150
PB - BMC
DO - 10.1186/
UR - https://
LA - en
ER -
CSL-JSON
{
"id": "10.1186/
"type": "article-journal",
"title": "Integrated analysis of single-cell transcriptome identifies a glial-neurovascular signaling trajectory in brain repair after ischemia",
"container-title": "Biology direct",
"author": [
{
"family": "Liu",
"given": "Hanyou"
},
{
"family": "Li",
"given": "Zhenwei"
},
{
"family": "Geng",
"given": "Ruxu"
},
{
"family": "Gu",
"given": "Lingui"
},
{
"family": "Bao",
"given": "Xinjie"
}
],
"container-title-short":
"volume": "21",
"issue": "1",
"page": "168",
"DOI": "10.1186/
"PMID": "42706574",
"PMCID": "PMC13548491",
"ISSN": "1745-6150",
"publisher": "BMC",
"URL": "https://
"language": "en",
"issued": {
"date-parts": [
[
2026,
9,
7
]
]
}
}
Similar papers
The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.
- [1] doi:10.1186/s13073-026-01687-x
- Infiltrating monocyte-derived macrophages does not survive long term in stroke brain despite their dominance in the acute ischemic core and myeloid derived IGF-1 play dichotomous roles in stroke recovery.Journal: Genome medicineIn common: stroke, genetics / omics, mouse, 1 other category, 5 references
- [2] doi:10.1126/sciadv.aed6825
- SORLA up-regulation suppresses pathological effects in aged tauopathy mouse brain.Journal: Science advancesIn common: genetics / omics, mouse, cellular / molecular, 7 references
- [3] doi:10.1038/s41593-026-02354-5 [code]
- Focal astrocyte loss reveals nuclear translocation during lesion repopulation.Journal: Nature neuroscienceIn common: mouse, cellular / molecular, 7 references
- [4] doi:10.1186/s12974-026-03794-3
- Single-cell omics and flow cytometry identify distinct immune states of dural and brain-infiltrating IL-17-producing γδ T cells after experimental stroke.Journal: Journal of neuroinflammationIn common: stroke, genetics / omics, mouse, 1 other category, 5 references
- [5] doi:10.1016/j.neurot.2026.e00977
- Exosome-mediated delivery of 3-n-butylphthalide rescues microglial energy crisis and ameliorates neuroinflammation in ischemic stroke.Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeuticsIn common: NCBI GEO GSE250245, stroke, mouse, cellular / molecular, 1 reference
- [6] doi:10.1038/s41467-026-70304-7
- NF-κB activation in astrocytes impairs wound healing after traumatic brain injury in male mice.Journal: Nature communicationsIn common: mouse, cellular / molecular, 5 references
- [7] doi:10.1038/s41593-026-02367-0 [code]
- A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes.Journal: Nature neuroscienceIn common: cellular / molecular, 7 references
- [8] doi:10.1186/s13024-026-00948-y
- Dual orexin receptor antagonism with lemborexant enhances microglial clearance of β-amyloid in mice.Journal: Molecular neurodegenerationIn common: genetics / omics, mouse, cellular / molecular, 5 references
- [9] doi:10.1186/s12974-026-03809-z
- Ependymal cell inflammatory activation in response to intracerebral hemorrhage.Journal: Journal of neuroinflammationIn common: stroke, genetics / omics, mouse, 1 other category, 5 references
- [10] doi:10.1038/s41467-026-72639-7
- Neuregulin-1 facilitates myelin regeneration through microglia-mediated mechanisms in a mouse model of chronic demyelination.Journal: Nature communicationsIn common: mouse, cellular / molecular, 4 references
Contribute
The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.
Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.
Claim this paper
Correct its record
Say what each link of this record is, remove the ones that are not the paper's, add the ones that are missing. The correction becomes a new version of the record, in its Versions section.
Request its removal
To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).
Discussion, reproductions, activity
Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.
Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.
Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.
