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A combination of ketones and NAD<sup>+</sup> precursor preserves white matter integrity in mild cognitive impairment.

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Paper

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The authors' code

License · 21 lines · 1.1 KB · MIT

  1. MIT License
  3. Copyright (c) 2019 Sherbrooke Connectivity Imaging Lab
  5. Permission is hereby granted, free of charge, to any person obtaining a copy
  6. of this software and associated documentation files (the "Software"), to deal
  7. in the Software without restriction, including without limitation the rights
  8. to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
  9. copies of the Software, and to permit persons to whom the Software is
  10. furnished to do so, subject to the following conditions:
  12. The above copyright notice and this permission notice shall be included in all
  13. copies or substantial portions of the Software.
  15. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
  16. IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
  17. FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
  18. AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
  19. LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
  20. OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
  21. SOFTWARE.

LICENSE at commit bd2fb4b, under MIT · at the source

Overview

Authors: Maggie Roy1, Mélanie Fortier1, Valérie St‐Pierre1, Marie‐Christine Morin1, Arnaud Boré2, Manon Edde2, Camille Vandenberghe2, Karine Groulx1, Étienne Croteau3,4, Gabriel Richard3,4, Stanislas Thoumyre2, Tamas Fulop1,5, Christian Bocti1,5, François Rheault2, Bernard Cuenoud3,5, Maxime Descoteaux2, Stephen C. Cunnane1,5
ORCID iDs: Maggie Roy
  1. Research Center on Aging CIUSSS de l'Estrie ‐ CHUS Sherbrooke Quebec Canada
  2. Sherbrooke Connectivity Imaging Lab (SCIL) Université de Sherbrooke Sherbrooke Quebec Canada
  3. CR‐CHUS CIUSSS de l'Estrie ‐ CHUS Sherbrooke Quebec Canada
  4. Sherbrooke Molecular Imaging Center Université de Sherbrooke Sherbrooke Quebec Canada
  5. Department of Medicine Université de Sherbrooke Sherbrooke Quebec Canada
Institutions: Centre Hospitalier Universitaire de Sherbrooke (Canada); Université de Sherbrooke (Canada)
Journal: Alzheimer's & dementia (New York, N. Y.), volume 12, issue 2, article e70278
Dates: received 23 February 2026; accepted 8 May 2026; published online 22 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1002/trc2.70278 · PMID 42344884 · PMCID PMC13286740 · OpenAlex W7165516732
Open access: gold, a free copy (OpenAlex)
Status: empty repository
Categories: structural MRI / diffusion (modality), PET / SPECT (modality), Alzheimer's / dementia (population), cellular / molecular (subfield)
Methods: Connectivity, Statistics, fMRI & imaging
Keywords: Alzheimer's disease, beta‐hydroxybutyrate, brain metabolism, diffusion MRI, FDG, ketogenic supplement, ketone, mild cognitive impairment, myelin, MTR, NAD, processing speed, PET imaging, tractography, white matter
Topic: Advanced MRI Techniques and Applications (Radiology, Nuclear Medicine and Imaging, Medicine), according to OpenAlex
Funding: Alzheimer's Association (PTC‐19‐605‐742); Nestlé Health Science; Faculté de médecine et des sciences de la santé, Université de Sherbrooke (Research Chair in Ketotherapeutics)
Citations: not cited yet (Europe PMC); 50 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Repository

Its files are read in the Code ↔ Paper reader above.

scilus/rbx_flow

License: MIT
State: the link answers, verified on 28 September 2026
Evidence: files inventoried
Commit: bd2fb4bd6d745603d048fa249af98083b397e022, 24 June 2025
Size: 6 files, 0 scripts
Software Heritage: not archived
Found in: the text, “Diffusion MRI”
Holds: README, license file
Not found: CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 28 September 2026: the link answers
  • 28 September 2026: the link answers
2 files
At the source: github.com/scilus/rbx_flow

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 17 authors, 15 keywords, 3 funders, 48 references.

Cite

This paper

Roy, M., Fortier, M., St‐Pierre, V., Morin, M., Boré, A., Edde, M., Vandenberghe, C., Groulx, K., Croteau, É., Richard, G., Thoumyre, S., Fulop, T., Bocti, C., Rheault, F., Cuenoud, B., Descoteaux, M., & Cunnane, S. C. (2026). A combination of ketones and NAD<sup>+</sup> precursor preserves white matter integrity in mild cognitive impairment. Alzheimer's & dementia (New York, N. Y.), 12(2), e70278. https://doi.org/10.1002/trc2.70278

BibTeX

@article{roy2026combination,
author = {Roy, Maggie and Fortier, Mélanie and St‐Pierre, Valérie and Morin, Marie‐Christine and Boré, Arnaud and Edde, Manon and Vandenberghe, Camille and Groulx, Karine and Croteau, Étienne and Richard, Gabriel and Thoumyre, Stanislas and Fulop, Tamas and Bocti, Christian and Rheault, François and Cuenoud, Bernard and Descoteaux, Maxime and Cunnane, Stephen C.},
title = {{A combination of ketones and NAD\<sup\>+\</sup\> precursor preserves white matter integrity in mild cognitive impairment}},
journal = {Alzheimer's \& dementia (New York, N. Y.)},
year = {2026},
month = apr,
volume = {12},
number = {2},
pages = {e70278},
publisher = {Wiley},
issn = {2352-8737},
doi = {10.1002/trc2.70278},
url = {https://doi.org/10.1002/trc2.70278},
pmid = {42344884},
pmcid = {PMC13286740}
}

RIS

TY - JOUR
AU - Roy, Maggie
AU - Fortier, Mélanie
AU - St‐Pierre, Valérie
AU - Morin, Marie‐Christine
AU - Boré, Arnaud
AU - Edde, Manon
AU - Vandenberghe, Camille
AU - Groulx, Karine
AU - Croteau, Étienne
AU - Richard, Gabriel
AU - Thoumyre, Stanislas
AU - Fulop, Tamas
AU - Bocti, Christian
AU - Rheault, François
AU - Cuenoud, Bernard
AU - Descoteaux, Maxime
AU - Cunnane, Stephen C.
TI - A combination of ketones and NAD<sup>+</sup> precursor preserves white matter integrity in mild cognitive impairment
T2 - Alzheimer's & dementia (New York, N. Y.)
J2 - Alzheimers Dement (N Y)
PY - 2026
DA - 2026/04/01
VL - 12
IS - 2
SP - e70278
SN - 2352-8737
PB - Wiley
DO - 10.1002/trc2.70278
UR - https://doi.org/10.1002/trc2.70278
LA - en
ER -

CSL-JSON

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